About Us : FIBREGA

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Do humans have the capacity to regenerate?

We have witnessed the powerful effects of FIBREGA and PRG Pharma Pvt Ltd, officially announced the development of the world's first commercial Fibronectin (FIBREGA) which will benefit the construction of cell regeneration and repair. The basic components of FIBREGA regulate a dynamic balance between the cell and its extracellular matrix by constructing a microenvironment for the cell to regenerate.The main objective of FIBREGA is to regenerate and heal, which contributes to the patient's treatment for the fastest recovery.

Getting into FIBREGA

Fibronectin is a high-molecular-weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans).” (referred by Wikipedia) With the help of our scientific research and development, PRG Pharma Pvt Ltd has successfully developed a formula that helps a lot of patients to recover their lost life and skin. Without FIBREGA, wound regeneration and healing would not be possible.

As Without FIBREGA,

wound regeneration healing would not be possible


Is A New Concept

Products Details
Active Ingredient Plasma Fibronectin
Dosage Form Topical Sterile Spray
SKU 0.5mg/ml
Pack Size 10 ML.
Storage 2 to 8 degree celsius and 25 degree celsius
Shelf Life 18 months (2 to 8 degree Celsius) and 6 months (25 degree Celsius)

Why does a wound become chronic?

As evident, the underlying mechanisms for acute and chronic wounds are fundamentally same and the cells, proinflammatory mediators and proteases involved are essentially similar. However, the “wound healing” process seizes and the cycle gets stuck in the inflammation phase thus leading to a defective ECM formation and subsequent development of a chronic ulcer.

All the above mechanisms ultimately result in generation of excessive ROS by activated inflammatory cells, overproduction of proteolytic enzymes(MMPs) and inflammation which cause protein & tissue destruction and disintegration of the dermis; the wound then enters a repetitive cascade of events which can be clinically observed. However, “healing” process is stopped due to destruction of the only protein responsible for this process, Fibronectin.

Apart from all the factors including cells, proteins, signalling molecules, the only protein which is most consistently degraded and destroyed in any chronic ulcer is Fibronectin.

Without Fibronectin, Healing Cannot Occur.

Several studies have proved that despite having sufficient quantity of Fibronectin in Blood and Plasma, the chronic wound site was completely devoid of viable FN which upon replenishment by topical application lead to “reactivation” of healing process.

How FIBREGA can help patients achieve SUPERIOR outcome?

Since Fibronectin is involved in every stage of wound healing, it complements the existing therapies available based on its unique mechanism of action.

FIBREGA has shown synergistic outcomes with following therapy areas:

  • Topical Antimicrobial Therapy
  • Advanced wound care dressings
  • Grafting and Flapping Techniques.
  • Routine Debridement and Cleaning Technique.